Cocaine reshapes the plasticity of ventral hippocampus inputs onto nucleus accumbens medium spiny neurons, and reversal of this plasticity impairs cocaine seeking.Cocaine may be remodeling vHPC neurons through altered gene expression and cell excitability to drive cocaine reward and seeking behavior

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As of late February, there's no official word that an Amazon Big Spring Sale is happening in 2026. But that's not unpromising. Amazon didn't announce dates for its 2025 Spring Sale until March 18 — just a week before the start of the sale.

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